Weight Management

What Is Metabolic Support? Understanding GLP-1, Appetite and Healthy Weight Management

what is metabolic support? understanding GLP-1 and advanced metabolic support supplement

AWhat Does Metabolic Support Really Mean?

Metabolism is a network of processes that control how your body uses food for energy, responds to carbohydrates and fats, regulates appetite and maintains body composition and overall weight.

Metabolism is closely connected to everyday lifestyle factors. Sleep, stress, meal patterns, movement, hormones and gut health can all affect how hungry you feel, how satisfied you are after eating and how easy it is to maintain healthy habits. One of the easiest ways to improve metabolism is to eat wholefoods which naturally contain high fibre. However, in today’s world of ultra-processed foods which often have little fibre, achieving consistent, healthy eating habits can be challenging.

Advanced Metabolic Support brings together three researched ingredients, Metabolaid®, Morosil® red orange extract and berberine, to support appetite awareness, healthy metabolic function and body composition. It is not about harsh restriction, skipping meals or chasing quick fixes. It is about working with the body’s own systems to gently nudge metabolism in the right direction.

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The Science of Feeling Satisfied

You have probably heard plenty about GLP-1 in recent years. GLP-1, short for glucagon-like peptide-1, is a hormone that your body naturally produces after you eat. Its role is to help coordinate your body’s response to food. It does this by supporting insulin release, slowing the movement of food through the stomach and sending a message to the brain that you are becoming full.

We often hear about the concept of food noise. Food noise is when thoughts about food and eating become intrusive and are present irrespective of whether you’re hungry or not.  People who suffer from food noise report that they continue to think about food even after they’ve had a meal. GLP-1 is the key hormone that quietens food noise. It spurs on that feeling of comfortable satisfaction after a meal – also known as satiety.

When appetite signals are working well, it’s easier to eat in a calm and consistent way. You can still enjoy food and feel hungry when it’s time to eat, without feeling like thoughts about food or cravings are constantly competing for your attention.

GLP-1 medications like Ozempic work by supplying a potent, synthetic version of GLP-1 which binds to receptors in the body, eliciting a profound reduction in appetite. Users of GLP-1 medications tend to lose significant weight, but often with unpleasant side-effects. As well as coming with side effects, the synthetic approach to appetite control completely overrides the body’s own appetite control signals.

We developed Advanced Metabolic Support for those who prefer a more gentle, natural approach to supporting metabolic health and appetite control. One of the hero ingredients in this new supplement is called Metabolaid®. It is a patented blend of lemon verbena and hibiscus flower extracts. It supports the body’s own GLP-1 response, rather than acting like a pharmaceutical GLP-1 medicine.

The research is particularly interesting because the effect can be measured relatively quickly. In a clinical study, Metabolaid® increased GLP-1 secretion by 13% just 15 minutes after it was taken. After two months of supplementation, GLP-1 levels increased by more than 60% compared with placebo, without participants following a special diet or exercise programme.

Unlike a prescription GLP-1 medication, Metabolaid® can support feelings of fullness by working with normal biological processes, rather than overriding them.


A Healthier Relationship with Food

Appetite suppressants are presented as simply making you less hungry. But appetite is not the enemy. Hunger is a normal body signal, and trying to silence it is rarely helpful or sustainable.

A better goal is to feel more in control around food. That can mean feeling satisfied after meals, having fewer intense cravings, making food decisions with greater confidence and being less likely to turn to food when emotions are running high.

This was reflected in an eight-week consumer study of 112 adults taking Metabolaid®. Participants reported improvements in their day-to-day relationship with food, including healthier eating habits, reduced hunger and cravings, and improvements in overall appetite. Motivation improved, while emotional eating reduced over the course of the study.

One particularly encouraging result was consistency with healthy daily habits. At the beginning of the study, 34% of participants reported consistency with those habits. By week eight with Metabolaid®, that figure had risen to more than 70%.

This is an important distinction. The aim is not simply to eat less. It is to make healthier habits feel more achievable and maintainable, whether that means preparing a balanced breakfast, choosing a satisfying lunch or pausing before an emotionally driven snack.

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What is Berberine?

You may have heard a lot about berberine and wondered what it actually is. Berberine is a naturally occurring compound found in several plants, and it has been widely researched for its role in metabolic health.

Among the better-known berberine benefits is its support for healthy glucose metabolism, insulin response and blood-fat balance. Berberine also supports AMPK, an enzyme that controls the way cells sense and manage energy.

AMPK is an important part of the body’s energy-management system. When it is activated, it helps cells use available energy efficiently, including energy from carbohydrates and fats. That is why AMPK is described as a master metabolic switch.

Berberine is sometimes called “nature’s Ozempic”, but this is not an accurate comparison. Berberine does not work like a GLP-1 drug, and it is not a substitute for prescribed medication. Its role in Advanced Metabolic Support is to complement the formula’s broader focus on metabolic balance.


A Closer Look at Body Composition

The third key ingredient in Advanced Metabolic Support is Morosil®, an extract from Moro blood oranges grown in Italy. These richly coloured oranges contain anthocyanins, naturally occurring plant compounds that give red and purple fruits their vibrant colour.

Morosil® has been studied for its ability to support healthy body composition. In a six-month clinical study involving 102 adults, Morosil® supplementation was associated with reductions in waist and hip circumference, as well as improvements in abdominal, visceral (around the organs) and subcutaneous fat measures compared with placebo. Importantly, lean muscle mass was maintained.

Lean muscle matters. It supports strength, mobility, healthy ageing and the body’s ability to use energy effectively. For that reason, body composition can be a more useful measure of progress than body weight alone.

Morosil® works in part through inhibiting adipogenesis, the biological process through which precursor cells develop into fat cells. Research suggests Morosil® helps regulate genes involved in this process, helping to reduce the formation of new fat cells.

There is no miracle fat burner, and no supplement can replace nourishing food, movement, sleep or medical advice. But ingredients with a clear role in appetite, energy metabolism and body composition can be useful tools within a realistic, long-term health routine.

Advanced Metabolic Support is designed for adults who want more support with healthy eating patterns, feelings of fullness and metabolic balance. Take two capsules daily with food, ideally before a main meal, and allow consistency to do its work.

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REFERENCES

Boix-Castejón, M., et al. (2021). Effect of metabolaid® on pre- and stage 1 hypertensive patients: A randomized controlled trial. Journal of Functional Foods, 84, 104583. https://doi.org/10.1016/j.jff.2021.104583

Briskey, D., et al. (2022). Effectiveness of “Moro” Blood Orange Citrus sinensis Osbeck (Rutaceae) Standardized Extract on Weight Loss in Overweight but Otherwise Healthy Men and Women—A Randomized Double-Blind Placebo-Controlled Study. Nutrients, 14(3), 427. https://doi.org/10.3390/nu14030427

Cardile, V., et al. (2015). Clinical evaluation of Moro (Citrus sinensis (L.) Osbeck) orange juice supplementation for the weight management. Natural Product Research, 29(23), 2256–2260. https://doi.org/10.1080/14786419.2014.1000897

Herranz-López, M., et al. (2019). Differential effects of a combination of Hibiscus sabdariffa and Lippia citriodora polyphenols in overweight/obese subjects: A randomized controlled trial. Scientific Reports, 9(1), 2999. https://doi.org/10.1038/s41598-019-39159-5

Lee, Y.-S., et al. (2018). Metabolaid® Combination of Lemon Verbena and Hibiscus Flower Extract Prevents High-Fat Diet-Induced Obesity through AMP-Activated Protein Kinase Activation. Nutrients, 10(9), 1204. https://doi.org/10.3390/nu10091204

Marhuenda, J., et al. (2020). A Randomized, Double-Blind, Placebo Controlled Trial to Determine the Effectiveness a Polyphenolic Extract (Hibiscus sabdariffa and Lippia citriodora) in the Reduction of Body Fat Mass in Healthy Subjects. Foods (Basel, Switzerland), 9(1), 55. https://doi.org/10.3390/foods9010055

Martínez-Rodríguez, A., et al. (2022). New App-Based Dietary and Lifestyle Intervention on Weight Loss and Cardiovascular Health. Sensors, 22(3), 768. https://doi.org/10.3390/s22030768

Martínez-Rodríguez, A., et al. (2024). Effectiveness of a Polyphenol-Enriched Blend on Weight Management and Metabolic Syndrome-Related Parameters in Healthy Overweight Adults. Applied Sciences, 14(9), 3882. https://doi.org/10.3390/app14093882

Serna, A., et al. (2022). Effectiveness of a polyphenolic extract (Lippia citriodora and Hibiscus sabdariffa) on appetite regulation in overweight and obese grade I population: An 8-week randomized, double-blind, cross-over, placebo-controlled trial. European Journal of Nutrition, 61(2), 825–841. https://doi.org/10.1007/s00394-021-02678-x

Silva, M., et al. (2022). Gut microbiome-modulating properties of a polyphenol-enriched dietary supplement comprised of hibiscus and lemon verbena extracts. Monitoring of phenolic metabolites. Journal of Functional Foods, 91, 105016. https://doi.org/10.1016/j.jff.2022.105016